Treatment Neoadjuvant Profile
This profile includes 29 data elements to capture main information on the neoadjuvant treatment (if applicable). The “MedicationRegimen” sub-profile (not shown here) groups the names of all neoadjuvant medications (up to 6) with the start and end dates.
| Data Element | Data Type | Description | Terminology | Required |
|---|---|---|---|---|
| isa_second_primary_neoadj | Boolean | This is or is not a therapy for a second primary cancer | N/A | Required |
| isa_third_primary_neoadj | Boolean | This is or is not a therapy for a third primary cancer | N/A | Required |
| neo_yn | Boolean | The patient received neoadjuvant therapy or not | N/A | Required |
| med_neoadj_ther_trial_yn | Boolean | The patient received neoadjuvant therapy in a clinical trial or not | N/A | Required |
| med_neoadj_ther_off_lab_yn | Boolean | The patient received an off-label neoadjuvant therapy | N/A | Required |
| neo1_therapy | CodeableConcept | The 1st medication of the neoadjuvant regimen | RxNorm | Required |
| neo2_therapy | CodeableConcept | The 2nd medication of the neoadjuvant regimen | RxNorm | Required |
| neo3_therapy | CodeableConcept | The 3rd medication of the neoadjuvant regimen | RxNorm | Required |
| neo4_therapy | CodeableConcept | The 4th medication of the neoadjuvant regimen | RxNorm | Required |
| neo5_therapy | CodeableConcept | The 5th medication of the neoadjuvant regimen | RxNorm | Required |
| neo6_therapy | CodeableConcept | The 6th medication of the neoadjuvant regimen | RxNorm | Required |
| neo1_sd | Date | The start date of the administration of the 1st medication of the neoadjuvant regimen | N/A | Required |
| neo1_ed | Date | The end date of the administration of the 1st medication of the neoadjuvant regimen | N/A | Required |
| neo2_sd | Date | The start date of the administration of the 2nd medication of the neoadjuvant regimen | N/A | Required |
| neo2_ed | Date | The end date of the administration of the 2nd medication of the neoadjuvant regimen | N/A | Required |
| neo3_sd | Date | The start date of the administration of the 3rd medication of the neoadjuvant regimen | N/A | Required |
| neo3_ed | Date | The end date of the administration of the 3rd medication of the neoadjuvant regimen | N/A | Required |
| neo4_sd | Date | The start date of the administration of the 4th medication of the neoadjuvant regimen | N/A | Required |
| neo4_ed | Date | The end date of the administration of the 4th medication of the neoadjuvant regimen | N/A | Required |
| neo5_sd | Date | The start date of the administration of the 5th medication of the neoadjuvant regimen | N/A | Required |
| neo5_ed | Date | The end date of the administration of the 5th medication of the neoadjuvant regimen | N/A | Required |
| neo6_sd | Date | The start date of the administration of the 6th medication of the neoadjuvant regimen | N/A | Required |
| neo6_ed | Date | The end date of the administration of the 6th medication of the neoadjuvant regimen | N/A | Required |
| neo_intent | CodeableConcept | The purpose of the neoadjuvant medication or regimen, either curative or palliative | SNOMED CT | Required if known |
| neo_discontinue | Boolean | The neoadjuvant medication or regimen discontinued or not | N/A | Required |
| neo_discontinue_reason | CodeableConcept | A code explaining unplanned or premature termination of the neoadjuvant medication or regimen | Code Set | Required |
| neo_toxicity | String | Explain the type of toxicity that led to neoadjuvant therapy discontinuation | N/A | Required |
| date_cur_treat_neoadj | Date | Date of curation | N/A | Required if known |
| cur_by_treat_neoadj | String | The name of the curator who modified the instrument | N/A | Required if known |
Notes
1. This profile is repeatable and more than one records can be expected per patient
2. The “Code Set” is a custom set of codes defined by the JHU Team