Assay Profile

This profile inlcudes 16 data elements to represent the molecular assay specifications.

Data Element	Data Type	Description	Terminology	Required
tumor_prof_report	Attachment	Upload tumor profiling report	N/A	Required
date_tumor_prof_rept	Date	The date/time this report was issued	N/A	Required
tumor_test_type	CodeableConcept	The method used to perform the genetic test. Examples include Fluorescent in situ hybridization (FISH), polymerase chain reaction-based assays (PCR), and next-generation sequencing (NGS).	Code Set	Required
tumor_prof_provider	CodeableConcept	The name of the organization producing the report	Code Set	Required
assay	CodeableConcept	The range(s) of the DNA sequence examined	Code Set	Required
other_assay	String	Additional description if “Other” is selected in the “Test Assay” question	N/A	Required
surg_path_id_assay	String	The ID number from the surgical pathology report	N/A	Required
tumor_prof_case_id	String	The tumor profiling case ID	N/A	Required
coverage	String	Sequencing depth	N/A	Required
tmb	Integer	The total number of mutations (changes) found in the DNA of cancer cells	N/A	Required
loh	String	The genomic loss of heterozygosity	N/A	Required
loh_assay	String	The assay loss of heterozygosity	N/A	Required
msi_status	CodeableConcept	Microsatellite status	Code Set	Required
msi_date	Date	MSI date	N/A	Required
date_cur_assay	Date	Date of curation	N/A	Required if known
cur_by_assay	String	The name of the curator who modified the instrument	N/A	Required if known

Notes

1. This profile is repeatable and more than one records can be expected per patient
2. The “Code Set” is a custom set of codes defined by the JHU Team